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Sigrid Egger (finished 2010)

Project
From the enzymatic mechanism to biocatalytic applications: dehydrogenases / reductases of AKR and LDR superfamily types

Thesis Committee
Bernd Nidetzky (Supervisor)
Albin Hermetter
Dr. Ulrike Wagner (IMB, KFUG)
Dr. Harald Pichler (IMBT, TUG)

Further Information
no files/links found

  Sigrid Egger
Institute of Biotechnology and Biochemical Engineering
Technische Universitšt Graz
Petersgasse 12/1
8010 Graz

e-Mail: sigrid.egger@TUGraz.at
phone: +43 316 873 8408
fax: +43 316 873 8434
web: http://www.cis.tu-graz.ac.at/biote/

Publications

  • Straganz, G.D. et al.: Kinetic and CD/MCD spectroscopic studies of the atypical, three-His-ligated, non-heme Fe2+ center in diketone dioxygenase: the role of hydrophilic outer shell residues in catalysis. Biochemistry 2010; 49 (5), 996-1004.


  • Egger, S. et al.: UDP-glucose dehydrogenase: structure and function of a potential drug target. Biochem Soc Trans 2010; 38 (5), 1378-1385.

  • Kratzer, R et al.: Whole-cell bioreduction of aromatic alpha-keto esters using Candida tenuis xylose reductase and Candida boidinii formate dehydrogenase co-expressed in Escherichia coli. Microb Cell Fact 2008; 7, 37.

  • Kratzer, R. et al.: Integration of enzyme, strain and reaction engineering to overcome limitations of baker's yeast in the asymmetric reduction of alpha-keto esters. Biotechnol Bioeng 2008; 101 (5), 1094-1101.

    Curriculum vitae

    Born in Austria
    Internal DK student, selected through DK hearing 2006, starting date: 1.6.2006


    Education

    1997 - 1998 2 semesters Biology at University of Graz
    1998 - 2005 Undergraduate education, Diplomstudium Technical Chemistry, University of Technology, Graz
    June 2006 PhD Course Metabolic Engineering and Systems Biology, Lyngby, Denmark, DTU

    Posters and Oral presentations

    07/ 2005 Biotrans 2005 7th International Symposium on Biocatalysis and Biotransformations (Delft, NL)
    01/ 2007 - 02/ 2007 Linz winter school and winter workshop
    05/ 2007 Graduate seminar 2007 DK Molecular Enzymology
    08/ 2008 236th ACS NAtional meeting 2008, Philadelphia, USA
    11/ 2008 Epigenetic mechanisms in health and disease - from Biology to Medicine, University of Oxford, UK
    02/ 2008 12. Österreichischer Kohlenhydrat-Workshop, Vienna, Austria

    Research stays

    09/ 2007 BOKU, Vienna, Austria
    11/ 2008 - 08/ 2009 SGC, University of Oxford, UK

    Professional Experience

    01/ 2003 Institute of Biochemistry, University of Technology Graz (lab project)
    09/ 2005 - 11/ 2005 Institute of Biotechnology and Biochemical Engineering, University of Technology, Graz, (diploma thesis)
    02/ 2006 - 05/ 2006 Institute of Biotechnology and Biochemical Engineering, University of Technology, Graz (project collaborator)


    Teaching activities

    SS 04 Tutor Institute of Biotechnology and Biochemical Engineering, University of Technology, Graz



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